Ben Shalom D
Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer-Sheva, 84105 Israel.
Conscious Cogn. 2000 Sep;9(3):457-60. doi: 10.1006/ccog.2000.0453.
The human self model suggests that the construct of self involves functions such as agency, body-centered spatial perspectivity, and long-term unity. Vogeley, Kurthen, Falkai, and Maieret (1999) suggest that agency is subserved by the prefrontal cortex and other association areas of the cortex, spatial perspectivity by the prefrontal cortex and the parietal lobes, and long-term unity by the prefrontal cortex and the temporal lobes and that all of these functions are impaired in schizophrenia. Exploring the connections between the prefrontal cortex and the construct of self, the present article extends the application of the self model to autism. It suggests that in contrast to schizophrenia, agency and spatial perspectivity are probably preserved in autism, but that, similarly to schizophrenia, long-term unity is probably impaired. This hypothesis is compatible with a model of neuropsychological dysfunction in autism in a neural network including parts of the prefrontal cortex, the temporal lobes, and the cerebellum.
人类自我模型表明，自我的构建涉及能动性、以身体为中心的空间视角以及长期统一性等功能。沃格利、库尔特恩、法尔凯和迈雷雷特（1999年）指出，能动性由前额叶皮质和其他皮质联合区支持，空间视角由前额叶皮质和顶叶支持，长期统一性由前额叶皮质和颞叶支持，且精神分裂症患者的所有这些功能都会受损。本文探讨前额叶皮质与自我构建之间的联系，将自我模型的应用扩展到自闭症。研究表明，与精神分裂症不同，自闭症患者的能动性和空间视角可能得以保留，但与精神分裂症类似，长期统一性可能受损。这一假设与包括前额叶皮质、颞叶和小脑部分的神经网络中自闭症神经心理功能障碍模型相符。
