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阿尔茨海默病及相关痴呆症的净成本:一项基于佐治亚州医疗补助受助者的人群研究。

The net cost of Alzheimer disease and related dementia: a population-based study of Georgia Medicaid recipients.

作者信息

Martin B C, Ricci J F, Kotzan J A, Lang K, Menzin J

机构信息

Department of Clinical and Administrative Sciences, University of Georgia, College of Pharmacy, Athens 30602, USA.

出版信息

Alzheimer Dis Assoc Disord. 2000 Jul-Sep;14(3):151-9. doi: 10.1097/00002093-200007000-00006.

DOI:10.1097/00002093-200007000-00006
PMID:10994656
Abstract

The objective of this study was to estimate the direct medical cost of Alzheimer disease (AD) and related dementia to the Georgia Medicaid program. A retrospective, cross-sectional, matched control group design was used. AD cases 50 years of age and older were identified by using International Classification of Diseases (9th edition, Clinical Modification) diagnosis codes from 1994 Georgia Medicaid administrative claims files. For every case, three age- and gender-matched non-AD controls were selected. Differences in average recipient Medicaid expenditures between cases and controls were estimated using weighted least squares regression analysis, adjusting for age, gender, race, Charlson comorbidity index, Medicare eligibility, and months of Medicaid eligibility. A total of 8,671 AD cases were identified (prevalence, 4.4%). The average adjusted annual Medicaid expenditure per AD recipient was $14,492 (U.S.). The net (i.e., excess) average annual Medicaid cost per AD recipient (i.e., the difference in adjusted mean expenditures between cases and controls) was estimated to be approximately $8,200. Excessive nursing home expenditures accounted for most of the additional cost of treating dementia (> 85%), although inpatient hospital, physician, outpatient, and prescription drug expenditures also were higher among patients with AD. Based on these estimates, Georgia Medicaid is projected to spend almost $70 million annually for AD and related dementia. The excessive cost attributable to AD poses a significant burden to the Georgia Medicaid program.

摘要

本研究的目的是估算阿尔茨海默病(AD)及相关痴呆症给佐治亚州医疗补助计划带来的直接医疗成本。采用了回顾性、横断面、匹配对照组设计。通过使用1994年佐治亚州医疗补助管理索赔文件中的国际疾病分类(第9版,临床修订版)诊断代码,确定了50岁及以上的AD病例。对于每个病例,选择了三名年龄和性别匹配的非AD对照。使用加权最小二乘回归分析估算病例组和对照组之间平均受助人医疗补助支出的差异,并对年龄、性别、种族、查尔森合并症指数、医疗保险资格和医疗补助资格月数进行了调整。共确定了8671例AD病例(患病率为4.4%)。每位AD受助人调整后的年均医疗补助支出为14492美元(美国)。每位AD受助人的净(即额外)年均医疗补助成本(即病例组和对照组调整后平均支出的差异)估计约为8200美元。痴呆症治疗的额外成本大部分来自过高的疗养院支出(>85%),不过AD患者的住院医院、医生、门诊和处方药支出也较高。根据这些估计,佐治亚州医疗补助计划预计每年为AD及相关痴呆症支出近7000万美元。AD导致的过高成本给佐治亚州医疗补助计划带来了巨大负担。

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