Nguyen N X, Langenbucher A, Viestenz A, Küchle M, Seitz B
Augenklinik und Poliklinik der Universität Erlangen-Nürnberg, Germany.
Graefes Arch Clin Exp Ophthalmol. 2000 Aug;238(8):642-6. doi: 10.1007/s004170000164.
Photorefrative keratectomy can be used to flatten the curvature of the anterior cornea and reduce the myopic refraction of the eye. This leads to unphysiological topographical changes of the cornea and may alter the conditions for examinations of corneal surface topography. The purpose of this study was to check for mutual agreement of three different methods of assessment of astigmatism before and after myopic photorefractive keratectomy (PRK).
Forty-seven eyes of 28 patients (age 32.7+/-6.6 years) following PRK using an 193-nm excimer laser were included in this study. 37 eyes were treated for pure myopia (-4.9+/-2.4 D) and 10 eyes for myopic astigmatism (sphere -2.0 to -7.0 D, cylinder -1.0 to -3.0 D). Preoperatively and at 18 months postoperatively, subjective refractometry, keratometry and topography analysis were performed. The axes of topographic and keratometric cylinder were standardized periodically (180 degrees) with respect to the refractive cylinder axis.
Pre- and postoperatively, the absolute astigmatism values correlated highly significantly between all three methods (P< or =0.001). The mean refractive cylinder was 0.65+/-0.61 D preoperatively and 0.46+/-0.41 D postoperatively (P=0.2). The mean keratometric astigmatism was 1.14+/-0.64 D before and 0.94+/-0.50 D after PRK treatment (P=0.2). Among the three methods, the mean topographic astigmatism was the highest (P<0.001) preoperatively (1.31+/-0.56 D) and postoperatively (1.21+/-0.52 D) (P=0.3). In eyes treated for pure myopia, no difference between pre- and postoperative refractive, keratometric and topographic astigmatism was detected (P>0.5). The axes of both topographic and keratometric astigmatism correlated highly significantly with the refractive cylinder axis (R> or =30.9, P<0.0001).
Up to 2 years after myopic PRK, the difference between refractive and keratometric astigmatism does not differ from the preoperative value, indicating an even corneal surface. The absolute astigmatism values and the cylinder axis correlated well between subjective and objective methods of astigmatism assessment. Thus, objective measurements may be helpful in determining the cylinder component of best spectacle correction after PRK. However, topographic analysis overestimates astigmatism values systematically before and after PRK.
准分子激光原位角膜磨镶术可用于使角膜前表面曲率变平并降低眼睛的近视屈光度。这会导致角膜出现非生理性的地形学改变,并可能改变角膜表面地形图检查的条件。本研究的目的是检验三种不同的散光评估方法在近视性准分子激光原位角膜磨镶术(PRK)前后的一致性。
本研究纳入了28例患者(年龄32.7±6.6岁)的47只眼睛,这些眼睛接受了193纳米准分子激光PRK治疗。37只眼睛为单纯近视(-4.9±2.4 D)接受治疗,10只眼睛为近视散光(球镜-2.0至-7.0 D,柱镜-1.0至-3.0 D)接受治疗。在术前及术后18个月进行主观验光、角膜曲率测量和地形图分析。将地形图和角膜曲率测量柱镜的轴相对于屈光柱镜轴定期标准化(180度)。
术前和术后,所有三种方法之间的绝对散光值均高度显著相关(P≤0.001)。术前平均屈光柱镜为0.65±0.61 D,术后为0.46±0.41 D(P = 0.2)。PRK治疗前平均角膜曲率散光为1.14±0.64 D,治疗后为0.94±0.50 D(P = 0.2)。在这三种方法中,术前(1.31±0.56 D)和术后(1.21±0.52 D)平均地形图散光最高(P<0.001)(P = 0.3)。在单纯近视治疗的眼睛中,术前和术后的屈光、角膜曲率和地形图散光之间未检测到差异(P>0.5)。地形图和角膜曲率散光的轴均与屈光柱镜轴高度显著相关(R≥30.9,P<0.0001)。
近视PRK术后长达2年,屈光性散光和角膜曲率性散光之间的差异与术前值无差异,表明角膜表面均匀。主观和客观散光评估方法之间的绝对散光值和柱镜轴相关性良好。因此,客观测量可能有助于确定PRK术后最佳眼镜矫正的柱镜成分。然而,地形图分析在PRK术前和术后均系统性地高估了散光值。