霍乱弧菌埃尔托生物型的一个菌株在体内获得R质粒的可能性。
Potential for in vivo acquisition of R plasmids by one strain of Vibrio cholerae biotype El tor.
作者信息
Davey R B, Pittard J
出版信息
Antimicrob Agents Chemother. 1975 Aug;8(2):111-6. doi: 10.1128/AAC.8.2.111.
The feces of five patients admitted to a hospital during an outbreak of cholera in Melbourne, Australia, in November 1972, were examined for the presence of tetracycline-resistant coliforms and tetracycline-resistant strains of Vibrio cholerae. Despite the abundance of tetracycline-resistant coliforms able to transfer this resistance to other strains of Escherichia coli, no tetracycline-resistant strains of V. cholerae were detected. In vitro transfer experiments using the V. cholerae strain responsible for the outbreak as recipient revealed that it was a particularly poor host for most R plasmids.
1972年11月在澳大利亚墨尔本霍乱暴发期间，对一家医院收治的5名患者的粪便进行了检测，以检查是否存在耐四环素的大肠菌群和霍乱弧菌的耐四环素菌株。尽管存在大量能够将这种耐药性转移至其他大肠杆菌菌株的耐四环素大肠菌群，但未检测到耐四环素的霍乱弧菌菌株。以引发此次暴发的霍乱弧菌菌株作为受体进行的体外转移实验表明，对于大多数R质粒而言，它是一种特别差的宿主。
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