Laatiri M A, Chehata S, Amouri A, Bouaouina N, Chatti S, Saad A, Ennabli S
Service d'Hématologie Clinique, CHU Farhat Hached de Sousse, Tunisie.
Tunis Med. 2000 Mar;78(3):167-71.
Between 1989 and 1996, 21 cases with acute non lymphoblastic leukemia (11 males and 10 females) were diagnosed in our institution. Median age was 9 years (range, 2-15 years). Leukocyte count was more than 50,109/l in 47% of cases. According to the French-American-British (FAB) criteria, 7 cases were classified M1, 10 cases were classified M2, 1 classified M4Eo and 3 classified M5. All patients were treated with "7 + 3" protocol and complete remission was achieved in 17 cases (80%), 2 cases (10%) failed to respond and 2 (10%) died during induction. Relapse was observed in 15 cases. The 3-year survival rate was 20% and the relapse-free-survival rate was 12% confirming the worse prognosis of this leukemia when treated with standard chemotherapy.
1989年至1996年期间，我院确诊了21例急性非淋巴细胞白血病患者（男11例，女10例）。中位年龄为9岁（范围2至15岁）。47%的病例白细胞计数超过50,109/升。根据法国-美国-英国（FAB）标准，7例为M1型，10例为M2型，1例为M4Eo型，3例为M5型。所有患者均采用“7 + 3”方案治疗，17例（80%）实现完全缓解，2例（10%）无反应，2例（10%）在诱导期死亡。15例出现复发。3年生存率为20%，无复发生存率为12%，这证实了采用标准化疗治疗这种白血病时预后较差。
Zotero 插件