Sanchis-Alfonso V, Roselló-Sastre E
Department of Orthopaedic Surgery, Hospital Arnau de Vilanova, Valencia, Spain.
Am J Sports Med. 2000 Sep-Oct;28(5):725-31. doi: 10.1177/03635465000280051801.
We evaluated 13 lateral retinacula excised at the time of Insall proximal realignments or isolated lateral retinacular releases performed in patients with isolated symptomatic patellofemoral malalignment recalcitrant to nonoperative treatment. Evaluation was performed by means of conventional histologic and immunohistochemical analysis for neural markers (S-100 protein, neurofilament protein, substance P, and neural growth factor). The observations reported here provide a neuroanatomic basis for anterior knee pain syndrome in active young patients with isolated symptomatic patellofemoral malalignment and support the clinical observation that the lateral retinaculum may have a key role in the origin of this pain as a result of increased neural growth factor production, which induces proliferation of nociceptive axons, mainly in a perivascular location.
我们评估了13例在因孤立性症状性髌股关节排列不齐而接受非手术治疗无效的患者进行Insall近端重新排列或孤立性外侧支持带松解时切除的外侧支持带。通过常规组织学和神经标志物（S-100蛋白、神经丝蛋白、P物质和神经生长因子）的免疫组织化学分析进行评估。本文报道的观察结果为患有孤立性症状性髌股关节排列不齐的活跃年轻患者的前膝痛综合征提供了神经解剖学基础，并支持临床观察，即外侧支持带可能在这种疼痛的起源中起关键作用，因为神经生长因子产生增加，这会诱导伤害性轴突增殖，主要在血管周围位置。
