对椎实螺（Lymnaea stagnalis L.）特定神经网络中脉冲序列和振荡的分析与调控
Analysis and modulation of spike trains and oscillations in identified neural network of Lymnaea stagnalis L.
作者信息
Molnár G, Szücs A, Rózsa K S
机构信息
Balaton Limnological Research Institute of the Hungarian Academy of Sciences, Tihany.
出版信息
Acta Biol Hung. 2000;51(2-4):231-5.
Identified neurons and members of functionally characterized clusters of the central nervous system of Lymnaea stagnalis L. were studied. Long-term spike trains (10-100 min) were collected using current clamp method. Firing patterns were analyzed by several mathematical tools e.g.: spike density function (SDF), interspike interval (ISI), Fourier-transform. Both the spike trains and oscillation of firing were modulated by 5HT (2 x 10(-5) M) and mu-opioid peptides (10(-5) M). Co-application of 5HT (2 x 10(-5) M) and DAGO (10(-5) M) turned the firing of the neurons (RPeD1 and A cells) opposite to the running pattern and eliminated the 0.3 Hz oscillation causing a new slow periodicity (0.1-0.05 Hz).
对椎实螺（Lymnaea stagnalis L.）中枢神经系统中已识别的神经元和功能特征性集群的成员进行了研究。使用电流钳方法收集长期的尖峰序列（10 - 100分钟）。通过几种数学工具分析放电模式，例如：尖峰密度函数（SDF）、峰峰间期（ISI）、傅里叶变换。5-羟色胺（5HT，2×10⁻⁵ M）和μ-阿片肽（10⁻⁵ M）均可调节尖峰序列和放电振荡。共同应用5HT（2×10⁻⁵ M）和DAGO（10⁻⁵ M）会使神经元（RPeD1和A细胞）的放电与运行模式相反，并消除0.3 Hz的振荡，从而产生新的慢周期（0.1 - 0.05 Hz）。
Zotero 插件