Sharp M, Bulsara M, Gollow I, Pemberton P
Neonatal Clinical Care Unit, Princess Margaret Hospital for Children, Perth, Western Australia, Australia.
J Paediatr Child Health. 2000 Oct;36(5):472-6. doi: 10.1046/j.1440-1754.2000.00552.x.
Population-based retrospective review of gastroschisis from 1986 to 1996.
This was a retrospective review of gastroschisis. Seventy cases were identified from the Birth Defects Registry of Western Australia (WA). Hospital medical records of live-born cases were reviewed.
The live-born incidence of gastroschisis in WA was 2.1 per 10,000 live births for the period 1986-96. The incidence in mothers aged less than 20 years was 8.3-fold that of women aged over 30 years (P < 0.0001). The incidence rate for the period 1995-96 was over twice the rate for 1986-88. Age at first enteral feed was significantly related with length of hospital stay and duration of total parental nutrition (TPN). Each day delay in commencing enteral feed was associated with an increase in hospital stay of 1.05 days and an increase in TPN duration of 1.06 days. The method of delivery of the infant, age at repair, length of anaesthetic time, duration of postoperative paralysis and gestational age was not associated with length of stay or TPN duration. The data were divided into two cohorts: (i) 1986-90; and (ii) 1991-96. There was a statistically significant reduction in hospital stay from a geometric mean of 45.7 (1986-90) to 22.9 days (1991-96).
Gastroschisis has a favourable outlook, with 89.7% survival of live births. Over the 10 year period studied, there has been a reduction in length of hospital stay and duration of TPN. The age at which the infant is first fed enteral feeds appears to be important in affecting the length of hospital stay and the duration of TPN, with delays associated with a longer hospital stay and longer TPN duration.
对1986年至1996年期间腹裂症进行基于人群的回顾性研究。
这是一项腹裂症的回顾性研究。从西澳大利亚州（WA）出生缺陷登记处识别出70例病例。对活产病例的医院病历进行了回顾。
1986 - 96年期间，WA腹裂症的活产发病率为每10000例活产中有2.1例。年龄小于20岁母亲的发病率是年龄大于30岁女性的8.3倍（P < 0.0001）。1995 - 96年期间的发病率是1986 - 88年期间发病率的两倍多。首次肠内喂养的年龄与住院时间和全胃肠外营养（TPN）持续时间显著相关。开始肠内喂养每延迟一天，住院时间增加1.05天，TPN持续时间增加1.06天。婴儿的分娩方式、修复时的年龄、麻醉时间长度、术后麻痹持续时间和孕周与住院时间或TPN持续时间无关。数据分为两个队列：（i）1986 - 90年；（ii）1991 - 96年。住院时间从几何平均数45.7天（1986 - 90年）显著减少至22.9天（1991 - 96年）。
腹裂症预后良好，活产儿存活率为89.7%。在研究的10年期间，住院时间和TPN持续时间有所减少。婴儿首次进行肠内喂养的年龄似乎对影响住院时间和TPN持续时间很重要，延迟喂养会导致住院时间延长和TPN持续时间延长。
