Josenhans W T, Peacocke T A, Schaller G
J Appl Physiol. 1975 Oct;39(4):541-7. doi: 10.1152/jappl.1975.39.4.541.
Two healthy males relaxing supine on a ballistobed were mechanically ventilated at positive end-expiratory pressures (PEEP) from 0 to 19 cmH2O. Pressures at the airway opening, middle esophagus, and stomach were monitored, together with tidal volume (VT) and ballistobed displacement. The effective elastance (i.e., sum of active and passive components) of the respiratory system (E'rs) and its components--abdominal muscle (E'ab), diaphragm (E'di), and rib cage (E'rc)--were calculated. With increasing PEEP, lung compliance increased slightly, E'rc and E'di decreased linearly, and E'ab increased linearly. The combined effective elastance of abdomen and diaphragm (E'ab+di) first decreased and then increased again. The abdomen-diaphragm contribution to VT during mechanical ventilation was approximately half that of spontaneous breathing.
两名健康男性仰卧在弹道床上，在呼气末正压（PEEP）为0至19 cmH₂O的情况下进行机械通气。监测气道开口、食管中部和胃部的压力，以及潮气量（VT）和弹道床位移。计算呼吸系统的有效弹性（即主动和被动成分之和）（E'rs）及其组成部分——腹肌（E'ab）、膈肌（E'di）和胸廓（E'rc）。随着PEEP的增加，肺顺应性略有增加，E'rc和E'di呈线性下降，E'ab呈线性增加。腹部和膈肌的联合有效弹性（E'ab+di）先下降后又再次上升。机械通气期间腹部-膈肌对VT的贡献约为自主呼吸的一半。
