Krieglstein G K
Klin Monbl Augenheilkd. 1975 Jul;167(1):55-61.
A group of 15 patients with chronic open angle glaucoma had been selected for this study. All of them were handicapped in the long-term self-medication of their antiglaucomatous eye drops either by visual function loss or by, physical or mental disorders. A preliminary test was made in each patient whether there was an essential difference in the therapeutic effect after self-medication and after optimal local application of the miotics by the doctor. Each of the selected patients had profile tonometry after self-medication, after medication by the observer and after Pilocarpine-Ocusert-P-40. There was evidence that the most pronounced therapeutic effect could be achieved by the correct placement of the antiglaucomatous drug in the individual eye. The results on the ocusert system indicate that pilocarpine ocuserts are advantageous over the incorrect placement of different miotics by the handicapped patient. The results had been statistically evaluated using the t-test. The possibilities of using the ocuserts in the elderly glaucoma patient are discussed.
本研究选取了15例慢性开角型青光眼患者。他们均因视力功能丧失或身体或精神障碍而在长期自行使用抗青光眼眼药水方面存在困难。对每位患者进行了一项初步测试,以确定自行用药后与医生进行最佳局部应用缩瞳剂后的治疗效果是否存在本质差异。每位入选患者在自行用药后、观察者用药后以及使用毛果芸香碱眼控释系统(Pilocarpine - Ocusert - P - 40)后均进行了轮廓眼压测量。有证据表明,通过在个体眼中正确放置抗青光眼药物可实现最显著的治疗效果。眼控释系统的结果表明,毛果芸香碱眼控释系统优于残疾患者错误使用不同缩瞳剂的情况。使用t检验对结果进行了统计学评估。讨论了在老年青光眼患者中使用眼控释系统的可能性。