Lambais M R, Goldman M H, Camargo L E, Goldman G H
Escola Superior de Agricultura 'Luiz de Queiroz', Universidade de São Paulo, Av. Pádua Dias 11, Cx.Postal 09, CEP 13.418-900 Piracicaba, São Paulo, Brazil.
Curr Opin Microbiol. 2000 Oct;3(5):459-62. doi: 10.1016/s1369-5274(00)00121-1.
Xylella fastidiosa is a fastidious, xylem-limited bacterium that causes several economically important plant diseases, including citrus variegated chlorosis (CVC). X. fastidiosa is the first plant pathogen to have its genome completely sequenced. In addition, it is probably the least previously studied of any organism for which the complete genome sequence is available. Several pathogenicity-related genes have been identified in the X. fastidiosa genome by similarity with other bacterial genes involved in pathogenesis in plants, as well as in animals. The X. fastidiosa genome encodes different classes of proteins directly or indirectly involved in cell-cell interactions, degradation of plant cell walls, iron homeostasis, anti-oxidant responses, synthesis of toxins, and regulation of pathogenicity. Neither genes encoding members of the type III protein secretion system nor avirulence-like genes have been identified in X. fastidiosa.
木质部难养菌是一种苛求的、局限于木质部的细菌，可引发多种具有重要经济影响的植物病害，包括柑橘杂色黄化病（CVC）。木质部难养菌是首个基因组被完全测序的植物病原体。此外，在所有已获得完整基因组序列的生物中，它可能是此前研究最少的。通过与植物及动物中其他参与致病过程的细菌基因进行相似性比较，在木质部难养菌基因组中已鉴定出多个与致病性相关的基因。木质部难养菌基因组编码了不同类型的蛋白质，这些蛋白质直接或间接参与细胞间相互作用、植物细胞壁降解、铁稳态、抗氧化反应、毒素合成以及致病性调控。在木质部难养菌中尚未鉴定出编码III型蛋白分泌系统成员的基因，也未发现类无毒基因。
