肥厚型心肌病或特发性扩张型心肌病患者血浆中 A 型和 B 型利钠肽水平
Plasma levels of A- and B-type natriuretic peptides in patients with hypertrophic cardiomyopathy or idiopathic dilated cardiomyopathy.
作者信息
Mizuno Y, Yoshimura M, Harada E, Nakayama M, Sakamoto T, Shimasaki Y, Ogawa H, Kugiyama K, Saito Y, Nakao K, Yasue H
机构信息
Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Honjo, Japan.
出版信息
Am J Cardiol. 2000 Nov 1;86(9):1036-40, A11. doi: 10.1016/s0002-9149(00)01147-4.
We investigated the relation between left ventricular structure and the secretion patterns of A- and B-type natriuretic peptides (ANP and BNP) by comparing their plasma levels in patients with hypertrophic cardiomyopathy (HC) and patients with idiopathic dilated cardiomyopathy (IDC). The secretion of ANP and BNP was much higher in patients with HC than in those with IDC; this shows that left ventricular cavity size is a key factor that regulates the secretion of ANP and BNP.
我们通过比较肥厚型心肌病（HC）患者和特发性扩张型心肌病（IDC）患者的血浆水平，研究了左心室结构与A、B型利钠肽（ANP和BNP）分泌模式之间的关系。HC患者中ANP和BNP的分泌比IDC患者高得多；这表明左心室腔大小是调节ANP和BNP分泌的关键因素。
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