Qasim A, Chauhan A, More R S
St. Mary's Hospital, Portsmouth, UK.
Int J Cardiol. 2000 Aug;75(1):5-14. doi: 10.1016/s0167-5273(00)00282-5.
Prompt treatment with thrombolytic therapy in acute myocardial infarction has been proven to reduce infarct size and mortality. However, reperfusion fails to occur in 30-50% of patients, either due to impaired epicardial artery flow or microvascular occlusion, with these patients experiencing a higher morbidity and mortality. We review the diagnosis and management of failed thrombolysis in acute myocardial infarction.