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嗜铬细胞瘤患者经皮心肺支持(PCPS)挽救地塞米松诱导的心源性休克

Dexamethasone-induced cardiogenic shock rescued by percutaneous cardiopulmonary support (PCPS) in a patient with pheochromocytoma.

作者信息

Takagi S, Miyazaki S, Fujii T, Daikoku S, Sutani Y, Morii I, Yasuda S, Goto Y, Nonogi H

机构信息

Division of Cardiology, National Cardiovascular Center, Fujishirodai, Suita, Japan.

出版信息

Jpn Circ J. 2000 Oct;64(10):785-8. doi: 10.1253/jcj.64.785.

Abstract

A 52-year-old man with pheochromocytoma had cardiogenic shock and was rescued using a percutaneous cardio pulmonary supporting system. After recovery, diagnostic tests including metaiodobenzylguanidine scintigraphy and computed tomography, revealed the pheochromocytoma which was confirmed by histology. It was postulated that the acute episode was induced by intra-joint dexamethasone, which increased the production of epinephrine and augmented the sensitivity of cardiomyocytes for catecholamine, thereby inducing the cardiomyopathy.

摘要

一名患有嗜铬细胞瘤的52岁男性发生心源性休克,使用经皮心肺支持系统进行了抢救。恢复后,包括间碘苄胍闪烁显像和计算机断层扫描在内的诊断测试发现了嗜铬细胞瘤,经组织学证实。据推测,急性发作是由关节内注射地塞米松引起的,地塞米松增加了肾上腺素的产生,并增强了心肌细胞对儿茶酚胺的敏感性,从而诱发了心肌病。

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