儿童复发性多软骨炎——病例报告及简要综述

Relapsing polychondritis in childhood--case report and short review.

作者信息

Knipp S, Bier H, Horneff G, Specker C, Schuster A, Schroten H, Lenard H G, Niehues T

机构信息

Department of Paediatrics, Heinrich Heine University of Duesseldorf, Germany.

出版信息

Rheumatol Int. 2000;19(6):231-4. doi: 10.1007/s002960000055.

DOI:10.1007/s002960000055

PMID:11063294

Abstract

Relapsing polychondritis (RP) is a disease of unknown etiology and it is characterized by inflammation of the cartilage. While the clinical picture of RP in adults is well described, RP in childhood is poorly documented. We describe a young girl presenting with acute dyspnea, stridor and polyarthritis. The diagnosis of RP was made 2 years after first presentation, when auricular chondritis occurred. Based on a MEDLINE search, reports on RP in childhood were reviewed. The frequency of chondritis and systemic manifestations of RP in children was compared to data in adults and found to be very similar. RP in childhood can be a life-threatening and debilitating disease.

摘要

复发性多软骨炎（RP）是一种病因不明的疾病，其特征是软骨炎症。虽然成人RP的临床表现已有详细描述，但儿童RP的文献记载较少。我们描述了一名出现急性呼吸困难、喘鸣和多关节炎的年轻女孩。在首次出现症状2年后，当耳廓软骨炎发生时，才确诊为RP。基于医学文献数据库（MEDLINE）搜索，对儿童RP的报告进行了综述。将儿童RP的软骨炎频率和全身表现与成人数据进行比较，发现非常相似。儿童RP可能是一种危及生命且使人衰弱的疾病。