Galen L W, Brower K J, Gillespie B W, Zucker R A
Department of Psychiatry and Alcohol Research Center, University of Michigan, Ann Arbor, MI 48108-3318, USA.
Drug Alcohol Depend. 2000 Dec 22;61(1):23-33. doi: 10.1016/s0376-8716(00)00125-3.
Antisocial personality disorder (ASPD) may predict poor prognosis but gender/sociopathy relationships to prognosis remain unclear. This study investigated the effects of ASPD upon psychiatric and substance-related outcomes among 235 addiction treatment center outpatients. Prevalence rates for ASPD were similar for males (16%) and females (22%). At baseline, women and ASPD patients displayed greater substance-related and psychiatric severity. At 6-month follow-up, ASPD patients had greater severity on both measures than did patients without ASPD, but women now had equivalent psychiatric severity to men. After controlling for initial severity, ASPD was related to worse substance-related outcomes, but not to worse psychiatric outcomes.
反社会人格障碍（ASPD）可能预示着预后不良，但性别/反社会人格与预后的关系仍不明确。本研究调查了ASPD对235名成瘾治疗中心门诊患者的精神和物质相关结局的影响。男性（16%）和女性（22%）的ASPD患病率相似。在基线时，女性和ASPD患者表现出更高的物质相关和精神严重程度。在6个月的随访中，ASPD患者在这两项指标上的严重程度均高于无ASPD的患者，但此时女性的精神严重程度与男性相当。在控制初始严重程度后，ASPD与更差的物质相关结局有关，但与更差的精神结局无关。
