Tisseau L, Zini L, Lemaitre L, Biserte J, Gosselin B, Leroy X
Service d'Anatomie et Cytologie Pathologiques, Hôpital Calmette, Lille, France.
Prog Urol. 2000 Sep;10(4):597-9.
Malakoplakia is a granulomatous inflammatory disorder occurring rarely in the prostate. We report our experience with three patients aged from 54 to 75 years old. Clinical presentations were unspecific. All patients presented with a past history of urinary tract infection. Ultrasound study revealed hypoechoic peripheral zone lesions. Histological examination showed a diffuse granulomatous inflammation with numerous histiocytes containing Michaelis-Gutmann bodies. In the prostate, malakoplakia is a histological variant of granulomatous chronic prostatitis following urinary infections. Clinically and radiologically, the differential diagnosis with adenocarcinoma is difficult. The symptoms disappear with a prolongated antibiotic treatment.
软斑病是一种罕见的发生于前列腺的肉芽肿性炎症性疾病。我们报告了3例年龄在54至75岁之间患者的诊治经验。临床表现不具特异性。所有患者均有尿路感染病史。超声检查显示外周带低回声病变。组织学检查显示弥漫性肉芽肿性炎症，有大量含有迈克尔is -古特曼小体的组织细胞。在前列腺中，软斑病是尿路感染后肉芽肿性慢性前列腺炎的一种组织学变异。在临床和放射学上，与腺癌进行鉴别诊断较为困难。症状通过延长抗生素治疗后消失。
