Seelig M H, Klingler P J, Oldenburg W A
Department of Surgery, General Hospital Ludwigshafen, Germany.
Eur J Surg. 2000 Oct;166(10):771-6. doi: 10.1080/110241500447399.
To evaluate the early and late outcome of mesenteric revascularisation in patients who had had elective mesenteric revascularisation for chronic intestinal ischaemia.
Retrospective review.
Academic clinic, United States.
19 consecutive patients (7 men, 12 women; mean age 70 years, range 53-83).
Angiography showed that 2 mesenteric vessels were affected in 7 patients and 3 in 12. Four patients had coexisting symptomatic aortoiliac occlusive disease and 1 patient had bilateral renal artery stenosis. A total of 36 visceral arteries were revascularised. One patient died postoperatively, and 8 developed serious complications. Morbidity and mortality were significantly higher in patients who had simultaneous infrarenal aortic or renal artery reconstructions (p = 0.01). Patients whose body weight before operation was less than 90% of ideal had more complications (8/11) than patients who were within 10% of their ideal body weight (1/8) (p = 0.02). Cumulative survival was 89% at 1 year, 72% at 3 years, and 57% at 5 years. The cumulative graft patency rate was 92% at 3 years and 66% at 5 years.
Mesenteric bypass procedures for chronic mesenteric ischaemia are durable. Long-term survival and graft patency rates are excellent even in older patients. Simultaneous aortic surgery should be avoided because of the associated morbidity. More than 10% below ideal body weight was associated with higher morbidity. For these patients, early total parenteral nutrition postoperatively, or a period of total parenteral nutrition preoperatively may reduce postoperative morbidity and mortality.
评估因慢性肠缺血接受择期肠系膜血管重建术患者的早期和晚期结局。
回顾性研究。
美国学术诊所。
19例连续患者(7例男性,12例女性;平均年龄70岁,范围53 - 83岁)。
血管造影显示,7例患者有2支肠系膜血管受累,12例患者有3支受累。4例患者同时存在有症状的主-髂动脉闭塞性疾病,1例患者有双侧肾动脉狭窄。共对36支内脏动脉进行了血管重建。1例患者术后死亡,8例发生严重并发症。同时进行肾下腹主动脉或肾动脉重建的患者的发病率和死亡率显著更高(p = 0.01)。术前体重低于理想体重90%的患者比体重在理想体重10%范围内的患者有更多并发症(8/11比1/8)(p = 0.02)。1年累计生存率为89%,3年为72%,5年为57%。3年累计移植物通畅率为92%,5年为66%。
慢性肠系膜缺血的肠系膜旁路手术效果持久。即使是老年患者,长期生存率和移植物通畅率也很高。由于相关的发病率,应避免同时进行主动脉手术。体重低于理想体重超过10%与更高的发病率相关。对于这些患者,术后早期全胃肠外营养或术前一段时间的全胃肠外营养可能会降低术后发病率和死亡率。