Greess H, Bentzien S, Gjuric M, Lell M, Lenz M, Bautz W
Institut für Diagnostische Radiologie, Friedrich-Alexander-Universität Erlangen-Nürnberg.
Rofo. 2000 Sep;172(9):753-8. doi: 10.1055/s-2000-7222.
To evaluate the ability of dynamic MRI to differentiate residual tumor from scar after glomus jugulare (GJ) surgery.
26 patients after GJ surgery were examined with dynamic contrast medium MRI on a 1.5 T Philips-Gyro-Scan NT. A T1-weighted TFE sequence was performed to localise the 5 slices for the dynamic study. Subsequently, a T1-weighted TFE sequence was used for the dynamic contrast medium study. We started contrast medium administration and TFE sequence at the same time. The time until acquisition of the first image was 7.4 s, and the interval between two images 7 s (total time 2.24 min). Intensity versus time studies were performed in the region of interest.
2 typical intensity versus time graphs were observed: residual tumors showed a rapid increase in signal intensity, followed by a "wash-out" phase, and a plateau phase in the later course. Scar showed a moderate increase in signal intensity, followed by a plateau phase on a low intensity level. In 9 patients, in whom tumor removal was subtotal, we saw the typical graph of a GJ tumor. 4 of 17 patients with complete tumor removal showed a typical graph like that of residual tumor, 13 of 17 patients showed the typical graph of a scar.
With dynamic contrast medium MRI studies, differentiation between residual tumor and scar is possible in patients with prior GJ surgery.
评估动态磁共振成像(MRI)鉴别颈静脉球瘤(GJ)手术后残留肿瘤与瘢痕的能力。
对26例GJ手术后患者采用1.5T飞利浦Gyro-Scan NT进行动态对比剂MRI检查。采用T1加权TFE序列定位5层进行动态研究。随后,使用T1加权TFE序列进行动态对比剂研究。我们在注射对比剂的同时启动TFE序列。获取第一张图像的时间为7.4秒,两张图像之间的间隔为7秒(总时间2.24分钟)。在感兴趣区域进行强度-时间研究。
观察到2种典型的强度-时间曲线:残留肿瘤表现为信号强度迅速增加,随后进入“廓清”期,后期为平台期。瘢痕表现为信号强度中度增加,随后在低强度水平进入平台期。在9例肿瘤切除不完全的患者中,我们看到了GJ肿瘤的典型曲线。17例肿瘤完全切除的患者中,4例表现出与残留肿瘤相似的典型曲线,13例表现出瘢痕的典型曲线。
通过动态对比剂MRI研究,GJ手术患者的残留肿瘤与瘢痕之间的鉴别是可行的。