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子宫内膜切除术后的子宫内膜腺癌。

Adenocarcinoma of the endometrium after endometrial ablation.

作者信息

Brooks-Carter G N, Killackey M A, Neuwirth R S

机构信息

Department of Obstetrics and Gynecology, St. Luke's-Roosevelt Hospital, New York, New York 10019, USA.

出版信息

Obstet Gynecol. 2000 Nov;96(5 Pt 2):836-7.

PMID:11094229
Abstract

BACKGROUND

Endometrial ablation is a relatively new technique for treating abnormal uterine bleeding not associated with malignancy. Long-term outcome data after endometrial ablation are limited, and incidence of endometrial adenocarcinoma after ablation is unknown.

CASE

A 55-year-old black woman who had endometrial ablation for abnormal uterine bleeding after excluding uterine cancer presented 5 years later with similar symptoms and a histologic diagnosis of well-differentiated adenocarcinoma of the uterus. She refused surgery and had radiation treatment for probable stage I endometrial adenocarcinoma.

CONCLUSION

It is unlikely in this high-risk patient that the endometrial ablation masked an undetected malignancy or delayed the diagnosis. Given the interval, the adenocarcinoma might have occurred de novo.

摘要

背景

子宫内膜消融术是一种治疗与恶性肿瘤无关的异常子宫出血的相对新技术。子宫内膜消融术后的长期结果数据有限,消融术后子宫内膜腺癌的发病率尚不清楚。

病例

一名55岁黑人女性,在排除子宫癌后因异常子宫出血接受了子宫内膜消融术,5年后出现类似症状,组织学诊断为高分化子宫腺癌。她拒绝手术,接受了针对可能的Ⅰ期子宫内膜腺癌的放射治疗。

结论

在这名高危患者中,子宫内膜消融术不太可能掩盖未被发现的恶性肿瘤或延迟诊断。考虑到时间间隔,腺癌可能是新发的。

相似文献

1
Adenocarcinoma of the endometrium after endometrial ablation.子宫内膜切除术后的子宫内膜腺癌。
Obstet Gynecol. 2000 Nov;96(5 Pt 2):836-7.
2
A case of endometrial cancer following endometrial ablation for dysfunctional uterine bleeding.
Obstet Gynecol. 1993 Oct;82(4 Pt 2 Suppl):640-2.
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Endometrial carcinoma after endometrial resection for dysfunctional uterine bleeding.因功能失调性子宫出血行子宫内膜切除术后发生的子宫内膜癌。
Obstet Gynecol. 2005 Nov;106(5 Pt 2):1174-6. doi: 10.1097/01.AOG.0000160484.20261.fd.
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Endometrial adenocarcinoma following endometrial ablation for postmenopausal bleeding.绝经后出血行子宫内膜切除术后发生的子宫内膜腺癌。
Gynecol Oncol. 1995 Mar;56(3):460-3. doi: 10.1006/gyno.1995.1083.
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Endometrial adenocarcinoma after endometrial ablation. A case report.
Eur J Gynaecol Oncol. 2006;27(4):432-3.
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Hysteroscopic surgery does not adversely affect the long-term prognosis of women with endometrial adenocarcinoma.宫腔镜手术不会对子宫内膜腺癌女性的长期预后产生不利影响。
J Minim Invasive Gynecol. 2007 Mar-Apr;14(2):205-10. doi: 10.1016/j.jmig.2006.10.010.
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Postablative risk of endometrial carcinoma in New Zealand white rabbits given high-dose estrogen.给予高剂量雌激素的新西兰白兔子宫内膜癌消融术后风险
J Reprod Med. 2000 Jul;45(7):553-6.
8
Endometrial adenocarcinoma arising in a secretory endometrium.
Gynecol Oncol. 1993 May;49(2):268-70. doi: 10.1006/gyno.1993.1122.
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Delayed leiomyoma degeneration after microwave endometrial ablation.微波子宫内膜切除术后平滑肌瘤延迟性退变
Obstet Gynecol. 2005 Nov;106(5 Pt 2):1176-8. doi: 10.1097/01.AOG.0000164068.18529.eb.
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Adenocarcinoma diagnosed at endometrial ablation.
Obstet Gynecol. 2001 May;97(5 Pt 2):837-9. doi: 10.1016/s0029-7844(00)01142-x.

引用本文的文献

1
Endometrial cancer after endometrial ablation vs medical management of abnormal uterine bleeding.子宫内膜切除术后的子宫内膜癌与异常子宫出血的药物治疗对比
J Minim Invasive Gynecol. 2014 Sep-Oct;21(5):744-52. doi: 10.1016/j.jmig.2014.02.012. Epub 2014 Feb 28.