Brooks-Carter G N, Killackey M A, Neuwirth R S
Department of Obstetrics and Gynecology, St. Luke's-Roosevelt Hospital, New York, New York 10019, USA.
Obstet Gynecol. 2000 Nov;96(5 Pt 2):836-7.
Endometrial ablation is a relatively new technique for treating abnormal uterine bleeding not associated with malignancy. Long-term outcome data after endometrial ablation are limited, and incidence of endometrial adenocarcinoma after ablation is unknown.
A 55-year-old black woman who had endometrial ablation for abnormal uterine bleeding after excluding uterine cancer presented 5 years later with similar symptoms and a histologic diagnosis of well-differentiated adenocarcinoma of the uterus. She refused surgery and had radiation treatment for probable stage I endometrial adenocarcinoma.
It is unlikely in this high-risk patient that the endometrial ablation masked an undetected malignancy or delayed the diagnosis. Given the interval, the adenocarcinoma might have occurred de novo.
子宫内膜消融术是一种治疗与恶性肿瘤无关的异常子宫出血的相对新技术。子宫内膜消融术后的长期结果数据有限,消融术后子宫内膜腺癌的发病率尚不清楚。
一名55岁黑人女性,在排除子宫癌后因异常子宫出血接受了子宫内膜消融术,5年后出现类似症状,组织学诊断为高分化子宫腺癌。她拒绝手术,接受了针对可能的Ⅰ期子宫内膜腺癌的放射治疗。
在这名高危患者中,子宫内膜消融术不太可能掩盖未被发现的恶性肿瘤或延迟诊断。考虑到时间间隔,腺癌可能是新发的。