Choi D H, Park N K, Cho H S, Hahm T S, Chung I S
Department of Anesthesiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-Dong, Kangnam-Ku, 135-710 Seoul, Korea.
Reg Anesth Pain Med. 2000 Nov-Dec;25(6):591-5. doi: 10.1053/rapm.2000.8934.
Epidural injection has been known to enhance spinal anesthesia in combined spinal and epidural (CSE) anesthesia. Saline and local anesthetics have been reported to have a volume effect, elevating sensory level when supplementing a volume into the epidural space. We evaluated the effects of epidural injection when using the CSE technique for cesarean delivery.
Sixty-six parturients were allocated randomly into group C (control, n = 21), S (saline, n = 21), or B (bupivacaine, n = 24): epidural injections of 10 mL saline and 0.25% bupivacaine were given in groups S and B, respectively, 10 minutes after they received 8 mg of 0.5% hyperbaric bupivacaine intrathecally, and no injection was given in group C. The sensory level at 10 minutes, the maximal level and the time to reach it, and degree of motor block and muscle relaxation were compared. We also investigated intraoperative side effects and postoperative findings in the postanesthesia care unit.
Epidural injection raised the sensory level significantly in groups S and B, but the maximal height of sensory block and degree of muscle relaxation did not differ among the groups. Fewer patients complained of intraoperative pain in group B than in the other groups (P <.001).
We could not achieve satisfactory surgical analgesia with 8 mg of hyperbaric bupivacaine injected into the subarachnoid space using the needle-through-needle technique in cesarean deliveries. An epidural saline injection elevated the sensory level, which did not improve the spinal block, whereas an epidural injection of 10 mL of 0.25% bupivacaine enhanced the spinal block and sustained the block postoperatively.
硬膜外注射已知可增强腰麻-硬膜外联合麻醉(CSE)中的腰麻效果。据报道,生理盐水和局麻药具有容量效应,向硬膜外腔补充一定容量时可提高感觉平面。我们评估了在剖宫产中使用CSE技术时硬膜外注射的效果。
66例产妇被随机分为C组(对照组,n = 21)、S组(生理盐水组,n = 21)或B组(布比卡因组,n = 24):S组和B组在蛛网膜下腔注射8 mg 0.5%重比重布比卡因10分钟后,分别给予10 mL生理盐水和0.25%布比卡因硬膜外注射,C组不进行注射。比较10分钟时的感觉平面、最高平面及达到该平面的时间、运动阻滞程度和肌肉松弛程度。我们还调查了术中副作用及麻醉后恢复室的术后情况。
硬膜外注射使S组和B组的感觉平面显著提高,但感觉阻滞的最高高度和肌肉松弛程度在各组间无差异。B组术中抱怨疼痛的患者少于其他组(P <.001)。
在剖宫产中采用针内针法于蛛网膜下腔注射8 mg重比重布比卡因无法实现满意的手术镇痛。硬膜外注射生理盐水可提高感觉平面,但未改善腰麻效果,而硬膜外注射10 mL 0.25%布比卡因可增强腰麻效果并在术后维持阻滞。