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低出生体重与氟斑牙:存在关联吗?

Low birth weight and dental fluorosis: is there an association?

作者信息

Kumar J V, Swango P A

机构信息

Bureau of Dental Health, New York State Department of Health, Albany, NY 12237-0619, USA.

出版信息

J Public Health Dent. 2000 Summer;60(3):167-71. doi: 10.1111/j.1752-7325.2000.tb03323.x.

Abstract

OBJECTIVE

The association between low birth weight and dental fluorosis was explored in a cross-sectional study to explain the higher prevalence of dental fluorosis among African-American children.

METHODS

Birth weight data on 960 children were obtained from the New York State Birth Registry. Data on race, fluoride exposure, sociodemographic characteristics, and dental fluorosis were available from a cross-sectional study conducted in Newburgh and Kingston. Associations among birth weight, race, and fluoride exposure from fluoridated water, regular use of supplements, brushing before the age of 2 years, and subject-level dental fluorosis were explored using logistic regression procedures.

RESULTS

The regression coefficients for the main effects and the two-way interaction effects associated with low birth weight, race, and fluoride exposure were not statistically significant. Even after controlling for low birth weight and fluoride exposure, African-American children had a statistically significant higher odds ratio (OR = 2.0). An analysis of the data limited to mandibular permanent first molars showed similar effects, except for evidence of effect modification in low birth weight children exposed to fluoride supplements.

CONCLUSIONS

Lower birth weight did not explain the higher prevalence of dental fluorosis observed among African-American children.

摘要

目的

在一项横断面研究中探讨低出生体重与氟斑牙之间的关联,以解释非裔美国儿童中氟斑牙患病率较高的原因。

方法

从纽约州出生登记处获取了960名儿童的出生体重数据。种族、氟暴露、社会人口学特征和氟斑牙的数据来自于在纽堡和金斯顿进行的一项横断面研究。使用逻辑回归程序探讨出生体重、种族以及来自氟化水的氟暴露、补充剂的经常使用、2岁前刷牙与个体水平氟斑牙之间的关联。

结果

与低出生体重、种族和氟暴露相关的主效应和双向交互效应的回归系数无统计学意义。即使在控制了低出生体重和氟暴露之后,非裔美国儿童的优势比(OR = 2.0)在统计学上仍显著更高。对仅限于下颌第一恒磨牙的数据进行分析显示了类似的结果,但在暴露于氟补充剂的低出生体重儿童中有效应修正的证据。

结论

较低的出生体重并不能解释在非裔美国儿童中观察到的较高的氟斑牙患病率。

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