正常人类肺部的生长与衰老。

Growth and aging of the normal human lung.

作者信息

Thurlbeck W M, Angus G E

出版信息

Chest. 1975 Feb;67(2 Suppl):3S-6S. doi: 10.1378/chest.67.2_supplement.3s.

DOI:10.1378/chest.67.2_supplement.3s

Abstract

The lung grows primarily by alveolar multiplication, but alveoli also double in size from infancy to adult life. The time at which alveolar multiplication ceases is obscure. As the lung ages it loses alveolar surface area due to alteration in the internal geometry of the lung. Alveolar wall tissue is also lost, thought to reflect loss of capillary bed.

摘要

肺主要通过肺泡增殖而生长，但从婴儿期到成年期，肺泡大小也会翻倍。肺泡增殖停止的时间尚不清楚。随着肺的老化，由于肺内部结构的改变，其肺泡表面积会减少。肺泡壁组织也会减少，这被认为反映了毛细血管床的减少。