用锝-99m亚甲基二膦酸盐对青少年皮肌炎钙质沉着症进行闪烁显像评估。

Scintigraphic evaluation of calcinosis in juvenile dermatomyositis with Tc-99m MDP.

作者信息

Bar-Sever Z, Mukamel M, Harel L, Hardoff R

机构信息

Department of Nuclear Medicine, Rabin Medical Center, Petach-Tikva, Israel.

出版信息

Clin Nucl Med. 2000 Dec;25(12):1013-6. doi: 10.1097/00003072-200012000-00012.

DOI:10.1097/00003072-200012000-00012

PMID:11129136

Abstract

Two children with juvenile dermatomyositis and extensive, debilitating soft tissue calcifications are described. Whole-body bone scans with Tc-99m MDP were performed in both cases before and during specific treatment for the calcinosis. Baseline studies showed marked tracer localization in the soft tissues and provided an objective baseline assessment of the extent of the soft tissue calcifications. Follow-up studies showed gradual clearance of the extraskeletal uptake and were useful in monitoring the therapeutic response. These cases show that skeletal scintigraphy can function as a useful auxiliary tool to evaluate calcinosis in children with juvenile dermatomyositis.

摘要

本文描述了两名患有青少年皮肌炎且伴有广泛、使人衰弱的软组织钙化的儿童。在针对钙质沉着症进行特定治疗之前和治疗期间，对这两名儿童均进行了锝-99m亚甲基二膦酸盐（Tc-99m MDP）全身骨扫描。基线研究显示示踪剂在软组织中有明显定位，并对软组织钙化的程度提供了客观的基线评估。随访研究显示骨骼外摄取逐渐清除，且有助于监测治疗反应。这些病例表明，骨骼闪烁显像可作为评估青少年皮肌炎患儿钙质沉着症的有用辅助工具。