Lamy C, Derambure P, Josien E, Destee A, Vermesch P, Leduc V, Steinling M
Service de Neurologie, CH de Béthune.
Rev Neurol (Paris). 2000 Dec;156(12):1113-9.
Ictal SPECT is a valuable method for the presurgical exploration of partial epilepsy. (99m)Tc Ethyl Cysteinate Dimer stable during 6h has contributed to develop ictal studies to evaluate the location of partial seizure. The aim of this study was to investigate some factors playing a possible role on the regional increase of cerebral blood flow (rCBF) Twenty-three patients with refractory partial epilepsy (temporal epilepsy n=16, extratemporal epilepsy n=7) were included. All the patients underwent a presurgical evaluation (phase I) during a week with detailed clinical history, cranial magnetic resonance imaging, monitoring EEG and video. Ictal and interictal SPECT were performed using a fast rotating brain dedicated camera (TOMOMATIC 564) in a quiet and normally illuminated room with controlled EEG (interictal) or video EEG (ictal); Scanning was started one hour after injection of ECD Tc administered in IV a few seconds after the electrical onset seizure. Slices parallel to the long axis of the temporal lobe were reconstructed. SPECT images were evaluated after normalisation. This study shows that
发作期单光子发射计算机断层扫描（ictal SPECT）是用于部分性癫痫术前评估的一种有价值的方法。6小时内稳定的（99m）锝半胱氨酸乙酯二聚体有助于开展发作期研究以评估部分性癫痫发作的部位。本研究的目的是调查一些可能对脑局部血流（rCBF）区域性增加起作用的因素。纳入了23例难治性部分性癫痫患者（颞叶癫痫16例，颞叶外癫痫7例）。所有患者在一周内接受了术前评估（第一阶段），包括详细的临床病史、头颅磁共振成像、脑电图监测和视频监测。在安静且光照正常、脑电图（发作间期）或视频脑电图（发作期）受控的房间内，使用快速旋转的脑部专用相机（TOMOMATIC 564）进行发作期和发作间期SPECT检查；在癫痫发作电活动开始后几秒静脉注射ECD锝后一小时开始扫描。重建与颞叶长轴平行的层面。SPECT图像经归一化后进行评估。本研究表明
