Radat F
Unité de Traitement de la Douleur Chronique, Service de Neurologie, Hôpital Pellegrin, 33076 Bordeaux Cedex.
Rev Neurol (Paris). 2000;156 Suppl 4:4S62-7.
Headache patients seen in headache clinics, apart from pain and physical symptoms, commonly present psychological problems of anxio-depressive nature, and in some cases traits of a pathological personnality. It is thus worthwhile to review the present state of knowledge about the comorbidity of psychiatric disorders and migraine, tension type headache, chronic daily headache and transformed migraines. Migraine sufferers in particular have been investigated more thoroughly than patients with other types of headache. Several studies have been conducted on migraine sufferers in the general population diagnosed using well-defined criteria ("International Headache Society" and "American Psychiatric Association"). There is a consensus that migraine sufferers have a higher risk of anxio-depressive disorders than the general population. Some authors also found a higher risk of substance (alcohol, drugs) abuse in migraine sufferers, which is consistent with the abuse of pain-killers commonly noted in patients seen in headache clinics. The patients seen in such clinics are, therefore, not representative of the general population. The coexistence of anxiety and/or depression and analgesic abuse in headache patients has been little explored from an epidemiological point of view. The nature of the link between the two types of disorder remains unknown: cause and effect, common etiological factor. However, it is apparent that the anxio-depressive disorder and analgesic abuse worsens the prognosis of the headache condition and that the treatment of headache in the general sense needs to take account of the underlying psychiatric morbidity rather than be restricted to treatment of the headache per se.
在头痛诊所就诊的头痛患者,除了疼痛和身体症状外,通常还存在焦虑抑郁性质的心理问题,在某些情况下还具有病态人格特征。因此,回顾一下关于精神障碍与偏头痛、紧张型头痛、慢性每日头痛和转化型偏头痛共病的现有知识状况是很有必要的。特别是偏头痛患者比其他类型头痛的患者受到了更深入的研究。针对使用明确标准(“国际头痛协会”和“美国精神病学协会”)诊断出的普通人群中的偏头痛患者进行了多项研究。人们达成了共识,即偏头痛患者患焦虑抑郁障碍的风险高于普通人群。一些作者还发现偏头痛患者存在更高的物质(酒精、药物)滥用风险,这与头痛诊所中常见的患者滥用止痛药的情况相符。因此,在这类诊所就诊的患者并不代表普通人群。从流行病学角度来看,头痛患者中焦虑和/或抑郁与止痛药滥用的共存情况鲜有探讨。这两种障碍之间联系的性质仍然未知:是因果关系、共同病因因素。然而,很明显焦虑抑郁障碍和止痛药滥用会使头痛病情的预后恶化,而且一般来说头痛的治疗需要考虑潜在的精神疾病,而不是局限于头痛本身的治疗。