van Wijngaarden J K, Huisman J, van der Meer J W, Visser H K
Katholieke Universiteit, afd. Interne Geneeskunde, Nijmegen.
Ned Tijdschr Geneeskd. 2000 Nov 25;144(48):2297-301.
Since the second half of 1996 epidemiological data point to an increased incidence of pertussis in the Netherlands despite high levels of immunisation. This increased incidence and the availability of new, so called acellular vaccines provoked a critical reflection on the present immunisation policy against pertussis. The Dutch Health Council has recommended replacing the cellular vaccine by an acellular vaccine, and adapting the immunisation schedule.
自1996年下半年以来,荷兰的流行病学数据显示,尽管免疫接种率很高,但百日咳的发病率仍在上升。发病率的上升以及新型无细胞疫苗的出现引发了对当前百日咳免疫政策的批判性反思。荷兰卫生委员会建议用无细胞疫苗取代细胞疫苗,并调整免疫接种计划。