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使用电荷耦合器件成像系统测量人体鼻气道模型中的颗粒沉积模式。

Measurement of particle deposition patterns in a human nasal airway model using a Charge Coupled Device imaging system.

作者信息

Zwartz G J, Guilmette R A

机构信息

Lovelace Respiratory Research Institute, P.O. Box 5890, Albuquerque, New Mexico, 87185-5890.

出版信息

Biomed Sci Instrum. 1999;35:347-52.

PMID:11143376
Abstract

Charge Coupled Device (CCD) imaging technology is being applied to measure the spatial deposition patterns of inhaled aerosols in the nasal airway. The new technology allows the experimenter to measure local particle deposition patterns of different sized fluorescent particles at variable flow rates in a full-scale multi-section replica of a human nasal airway. Images of fluorescing particles on the exposed model have been taken with a CCD camera and combined to form three-dimensional particle deposition patterns. Total particle deposition efficiencies and particle deposition patterns have been measured in the nasal airway for 6 microns diameter particles and compared with published inhalation data.

摘要

电荷耦合器件(CCD)成像技术正被应用于测量鼻气道中吸入气溶胶的空间沉积模式。这项新技术使实验者能够在人体鼻气道的全尺寸多节段复制品中,以可变流速测量不同大小荧光颗粒的局部颗粒沉积模式。用CCD相机拍摄暴露模型上荧光颗粒的图像,并将其组合以形成三维颗粒沉积模式。已测量了直径为6微米的颗粒在鼻气道中的总颗粒沉积效率和颗粒沉积模式,并与已发表的吸入数据进行了比较。

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