CD1d限制性小鼠Vα14和人Vα24 T细胞：天然免疫淋巴细胞
CD1d-restricted mouse V alpha 14 and human V alpha 24 T cells: lymphocytes of innate immunity.
作者信息
Benlagha K, Bendelac A
机构信息
Schultz Laboratory, Department of Molecular Biology, Princeton University, Princeton NJ 08544, USA.
出版信息
Semin Immunol. 2000 Dec;12(6):537-42. doi: 10.1006/smim.2000.0276.
PMID:11145859
Abstract
Mouse V alpha 14 T cells and their human homologs, V alpha 24 T cells, are prominent subsets of CD1d-restricted T cells. Here we discuss their striking similarities to B-1 B cells and gammadelta T cells and propose that these immune cells mediate various innate strategies in response to endogenous or exogenous danger signals.
摘要
小鼠Vα14 T细胞及其人类同源物Vα24 T细胞是CD1d限制性T细胞的主要亚群。在此，我们讨论它们与B-1 B细胞和γδ T细胞的显著相似性，并提出这些免疫细胞介导各种先天性策略以应对内源性或外源性危险信号。
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