Khaldi M, Mohamed S, Kallel J, Khouja N
Service de Neurochirugie, Institut National de Neurologie de Tunis, 1007 La Rabla, Tunis, Tunisia.
Childs Nerv Syst. 2000 Nov;16(10-11):765-9. doi: 10.1007/s003810000348.
Among a series of 155 brain hydatid disease patients hospitalized between 1965 and 1998, 117 were children. The mean age was approximately 7.2 years, with a slight male predominance. Eighteen patients presented with another visceral localization. Symptoms and signs of intracranial hypertension are currently encountered (75%) followed by hemiparesis, epilepsy, mental changes, skull deformities and, more rarely, dyskinetic phenomenon. Brain hemispheric localization is the rule, with some exceptions. CT scans reveal an intra-parenchymal lesion with clearly defined, rarely enhanced margins. Medical treatment has virtually no place in the management of cerebral solitary cyst. Albendazole has been used in cases of multiple involvement, with controversial results. Surgical hydrostatic expulsion is the only effective treatment. Recovery is expected when the cyst is extracted completely unruptured.
在1965年至1998年间住院的155例脑包虫病患者中,117例为儿童。平均年龄约为7.2岁,男性略占优势。18例患者伴有其他内脏部位受累。目前颅内高压的症状和体征最为常见(75%),其次是偏瘫、癫痫、精神改变、颅骨畸形,较少见的是运动障碍现象。脑半球受累是常见情况,但也有一些例外。CT扫描显示脑实质内病变,边界清晰,很少强化。药物治疗在孤立性脑囊肿的治疗中几乎没有作用。阿苯达唑已用于多发包虫病病例,但其结果存在争议。手术水压引流是唯一有效的治疗方法。若囊肿完整摘除,有望康复。