Durairaj L, Reilly B, Das K, Smith C, Acob C, Husain S, Saquib M, Ganschow P, Evans A, McNutt R
Department of Medicine, Cook County Hospital and Rush Medical College, Chicago, Illinois 60612, USA.
Am J Med. 2001 Jan;110(1):7-11. doi: 10.1016/s0002-9343(00)00640-9.
Little is known about physicians' use of inpatient cardiac telemetry units among emergency department patients at risk for cardiac complications. We therefore studied the outcomes of patients admitted to inpatient telemetry beds to identify a subset of patients from whom cardiac monitoring could be withheld safely.
We conducted a prospective cohort study of 1, 033 consecutive adult patients admitted to an inpatient telemetry unit from the emergency department of a 700-bed urban public teaching hospital. Subjects with or without chest pain were risk-stratified using a prediction rule and observed for in-hospital cardiac complications, acute myocardial infarction, and transfer to an intensive care unit (ICU).
There were no significant differences between patients with (n = 677) or patients without chest pain (n = 356) in the rates of major cardiac complications, myocardial infarctions, or transfers to an ICU. Among 318 patients with chest pain who were classified as being very low risk, none suffered major complications (negative predictive value 100%; 95% confidence interval [CI]: 98.8% to 100%). Among 214 very low risk patients without chest pain, 1 (0.5%) had a major complication (negative predictive value 99.5%; 95% CI: 97.4% to 99.9%).
The prediction rule accurately identified patients with or without chest pain who were at very low risk of major complications, identifying a subset from whom cardiac monitoring could be withheld safely.
对于急诊科有心脏并发症风险的患者,医生对住院心脏遥测单元的使用情况了解甚少。因此,我们研究了入住住院遥测病床患者的结局,以确定可以安全停止心脏监测的患者亚组。
我们对一家拥有700张床位的城市公立教学医院急诊科连续收治的1033例成年患者进行了前瞻性队列研究。使用预测规则对有或无胸痛的受试者进行风险分层,并观察其院内心脏并发症、急性心肌梗死以及转入重症监护病房(ICU)的情况。
有胸痛的患者(n = 677)与无胸痛的患者(n = 356)在主要心脏并发症、心肌梗死或转入ICU的发生率方面无显著差异。在318例被归类为极低风险的胸痛患者中,无一例发生主要并发症(阴性预测值为100%;95%置信区间[CI]:98.8%至100%)。在214例无胸痛的极低风险患者中,1例(0.5%)发生了主要并发症(阴性预测值为99.5%;95%CI:97.4%至99.9%)。
该预测规则准确识别出有或无胸痛且发生主要并发症风险极低的患者,确定了可以安全停止心脏监测的患者亚组。