Diaz-Buxo J A, Hermans P E, Elveback L R
Ann Intern Med. 1975 Feb;82(2):213-4. doi: 10.7326/0003-4819-82-2-213.
Twelve of 50 consecutive patients with idiopathic late-onset immunoglobulin deficiency had cholelithiasis. This represents a prevalence rate of 24%, which is significantly above the rate in a control group of 500 patients from this medical center matched 10:1 for age and sex (P less than 0.005). This finding adds a new gastrointestinal abnormality to those known to occur in idiopathic late-onset immunoglobulin deficiency.
50例连续性特发性迟发性免疫球蛋白缺乏患者中有12例患有胆结石。这代表患病率为24%,显著高于该医学中心500例年龄和性别按10:1匹配的对照组的患病率(P<0.005)。这一发现为已知在特发性迟发性免疫球蛋白缺乏中出现的胃肠道异常增加了一种新的异常情况。