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新生儿颅咽管瘤的根治性手术。病例报告。

Radical surgery in a neonate with craniopharyngioma. report of a case.

作者信息

Müller-Scholden J, Lehrnbecher T, Müller H L, Bensch J, Hengen R H, Sörensen N, Stockhausen H B

机构信息

Department of Pediatrics, University of Würzburg, Germany.

出版信息

Pediatr Neurosurg. 2000 Nov;33(5):265-269. doi: 10.1159/000055967.

Abstract

Ultrasonography revealed a suprasellar tumor in a fetus at 28 weeks of gestation. The male newborn, delivered 10 weeks later, was operated at the age of 17 days, and a craniopharyngioma was completely removed. Intraoperatively, inappropriate secretion of antidiuretic hormone occurred and was followed by diabetes insipidus causing imbalance of fluid and electrolytes. The tumor recurred and was totally removed 1 year later. Further development was uneventful and, at the age of 8 years, the boy is in generally good mental and physical condition except for a left-sided hemiparesis. In contrast to the poor outcome of neonatal craniopharyngioma reviewed in the literature, this case may encourage radical surgery even in the very young.

摘要

超声检查发现一名妊娠28周胎儿存在鞍上肿瘤。10周后出生的男婴在17日龄时接受了手术,颅咽管瘤被完全切除。术中出现抗利尿激素分泌不当,随后发生尿崩症,导致体液和电解质失衡。肿瘤复发,1年后再次被完全切除。后续发育正常,8岁时,除左侧偏瘫外,该男孩的精神和身体状况总体良好。与文献中所报道的新生儿颅咽管瘤的不良预后相反,该病例可能会促使人们即使对非常年幼的患儿也采取根治性手术。

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