骨髓移植后严重出血性膀胱炎行膀胱部分切除术加回肠膀胱扩大术。

Subtotal cystectomy with ileocystoplasty for severe hemorrhagic cystitis after bone marrow transplantation.

作者信息

Sèbe P, Garderet L, Traxer O, Nouri M, Gluckman E, Gattegno B

机构信息

Department of Urology, Hôpital Tenon, Paris, France.

出版信息

Urology. 2001 Jan;57(1):168. doi: 10.1016/s0090-4295(00)00882-7.

DOI:10.1016/s0090-4295(00)00882-7

PMID:11164170

Abstract

In a retrospective analysis of hemorrhagic cystitis subsequent to allogeneic bone marrow transplantation, we focused on patients who underwent subtotal cystectomy with ileocystoplasty because stepwise use of conservative treatments had failed. Severe lasting hemorrhagic cystitis (more than 40 days) led to urinary tract obstruction and sepsis that required subtotal cystectomy in 3 of 1300 bone graft patients. Hematuria did not recur after surgery with a satisfactory functional result (follow-up 10 months to 17 years). Subtotal cystectomy with detubularized ileocystoplasty can be used to control life-threatening hemorrhagic cystitis.

摘要

在一项对异基因骨髓移植后出血性膀胱炎的回顾性分析中，我们关注那些因逐步采用保守治疗失败而接受膀胱部分切除术并行回肠膀胱扩大术的患者。严重的持续性出血性膀胱炎（超过40天）导致尿路梗阻和脓毒症，在1300例骨移植患者中有3例需要进行膀胱部分切除术。术后血尿未复发，功能结果令人满意（随访时间为10个月至17年）。膀胱部分切除术并行去管化回肠膀胱扩大术可用于控制危及生命的出血性膀胱炎。