小儿患者下呼吸道细胞学标本评估中脂质性巨噬细胞的定量分析
Quantitation of lipid-laden macrophages in evaluation of lower airway cytology specimens from pediatric patients.
作者信息
Yang Y J, Steele C T, Anbar R D, Sinacori J T, Powers C N
机构信息
Department of Pathology, Upstate Medical University, State University of New York, 750 East Adams Street, Syracuse, NY 13210, USA.
出版信息
Diagn Cytopathol. 2001 Feb;24(2):98-103. doi: 10.1002/1097-0339(200102)24:2<98::aid-dc1018>3.0.co;2-t.
Quantitation of lipid-laden macrophages has been used as a tool in the diagnosis of aspiration-related respiratory disorders. Fifty-six respiratory specimens from pediatric patients with lung diseases were retrospectively reviewed, and lipid-laden macrophage indices were evaluated according to modified published grading methods. The indices from patients at high risk for aspiration were significantly different from those at low risk. A simpler and more reproducible grading method was introduced. An important issue regarding sample adequacy was also addressed.
脂质 laden 巨噬细胞的定量分析已被用作诊断与吸入相关的呼吸系统疾病的一种工具。对 56 例患有肺部疾病的儿科患者的呼吸标本进行了回顾性分析，并根据改良的已发表分级方法评估了脂质 laden 巨噬细胞指数。吸入高风险患者的指数与低风险患者的指数有显著差异。引入了一种更简单且更具可重复性的分级方法。还讨论了关于样本充足性的一个重要问题。
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