活体供体的多米诺式劈离式肝移植：原位和异位劈离的病例报告

Domino split-liver transplantation from a living donor: case reports of in situ and ex situ splitting.

作者信息

Inomata Y, Nakamura T, Uemoto S, Tanaka K, Wakabayashi G, Shimazu M

机构信息

Department of Transplantation and Immunology, Kyoto University, 54 Kawaracho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.

出版信息

Liver Transpl. 2001 Feb;7(2):150-3. doi: 10.1053/jlts.2001.21299.

DOI:10.1053/jlts.2001.21299

PMID:11172401

Abstract

The liver from a patient with familial amyloid polyneuropathy (FAP) scheduled for living donor liver transplantation can be split and transplanted into 2 adult patients with end-stage liver disease. We have performed this procedure, called domino split transplantation, twice. The native liver was split in situ in 1 patient with FAP and ex situ in the other patient with FAP. The recipients of the livers from the patients with FAP and their living donors are doing well without serious complications. Of the 4 secondary recipients, 3 patients survived. Domino split-liver transplantation from a living donor thus appears to be a promising procedure for expansion of the donor pool.

摘要

一名计划进行活体肝移植的家族性淀粉样多神经病（FAP）患者的肝脏可以被分割并移植给两名终末期肝病成年患者。我们已经进行了两次这种被称为多米诺分割移植的手术。在一名FAP患者中对其原生肝脏进行了原位分割，在另一名FAP患者中进行了异位分割。来自FAP患者肝脏的接受者及其活体供者情况良好，没有严重并发症。在4名二次接受者中，3名患者存活。因此，来自活体供者的多米诺分割肝移植似乎是一种扩大供体库的有前景的手术。