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放射性引导甲状旁腺手术的初步经验。

An initial experience with radioguided parathyroid surgery.

作者信息

Angelos P

机构信息

Department of Surgery, Division of General Surgery, Northwestern University Medical School, Chicago, Illinois, USA.

出版信息

Am J Surg. 2000 Dec;180(6):475-7; discussion 477-8. doi: 10.1016/s0002-9610(00)00512-2.

Abstract

BACKGROUND

Recent reports have shown the effectiveness of preoperative parathyroid scintiscanning as an aid to parathyroidectomy. Less attention has been paid to limitations of this approach based on patient characteristics.

METHODS

All patients evaluated for primary hyperparathyroidism by an endocrine surgeon from December 1, 1998, through October 31, 1999, were retrospectively reviewed. Data were gathered to determine which patients were candidates for the radioguided approach, the effectiveness of this approach, and the reasons why some patients were not candidates for this approach.

RESULTS

Thirty-three patients were evaluated. Based on history, 4 patients were not candidates for a radioguided approach. Of the remaining 29 patients, 19 had positive sestamibi scans (65.5%) and successful radioguided operations. The 10 patients (34.5%) with negative scans had successful standard parathyroidectomy.

CONCLUSION

Although radioguided parathyroid surgery is an effective surgical approach, only 57.6% of patients in this series could have a radioguided operation. Standard four-gland exploration will continue to be needed for many patients.

摘要

背景

近期报告显示术前甲状旁腺闪烁扫描有助于甲状旁腺切除术。基于患者特征,该方法的局限性较少受到关注。

方法

对1998年12月1日至1999年10月31日期间由内分泌外科医生评估原发性甲状旁腺功能亢进的所有患者进行回顾性研究。收集数据以确定哪些患者适合放射性引导手术,该方法的有效性以及一些患者不适合该方法的原因。

结果

共评估了33例患者。根据病史,4例患者不适合放射性引导手术。其余29例患者中,19例(65.5%) sestamibi扫描呈阳性且放射性引导手术成功。10例(34.5%)扫描阴性的患者标准甲状旁腺切除术成功。

结论

尽管放射性引导甲状旁腺手术是一种有效的手术方法,但本系列中只有57.6%的患者可以进行放射性引导手术。许多患者仍需要标准的四腺探查。

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