Chadli-Debbiche A, Ben Brahim E, Dougaz A, Mansouri D, Fraoua-Abdelmoula F, Mbarek A, Mamouri M, Mzabi-Regaya S
Service d'Anatomie et de Cytologie pathologiques, Hôpital Mongi Slim, La Marsa, Tunisie.
Tunis Med. 2000 Oct;78(10):607-12.
A case of polymorphous low-grade adenocarcinoma of minor salivary gland is reported. This tumor was first described in two clinical case series in 1983. Before that time most of these neoplasms were diagnosed as benign salivary gland neoplasms (pleomorphic adenomas) or salivary malignant conditions (malignant pleomorphic adenomas, adenoid cystic carcinomas, papillary adenocarcinomas and adenocarcinoma not otherwise stated). This neoplasm, with few exceptions, originates in minor salivary gland tissues of the palates or buccal mucosa. It is characteristically slow to enlarge. Clinical reports show the neoplasm present for many years before diagnosis. The tumor have a variety of morphological patterns, a cytological uniformity and an infiltration into adjacent structures. The treatment is a wide local excision. Recurrences and lymph node metastases are rare.
本文报告1例小涎腺多形性低度恶性腺癌。该肿瘤于1983年在两个临床病例系列中首次被描述。在此之前,这些肿瘤大多被诊断为涎腺良性肿瘤(多形性腺瘤)或涎腺恶性疾病(恶性多形性腺瘤、腺样囊性癌、乳头状腺癌及未特指的腺癌)。除少数例外,该肿瘤起源于腭部或颊黏膜的小涎腺组织。其特点是生长缓慢。临床报告显示,该肿瘤在诊断前已存在多年。肿瘤具有多种形态学模式、细胞一致性并浸润至邻近结构。治疗方法为广泛局部切除。复发和淋巴结转移少见。