Impact of oncogenes and tumor suppressor genes on deregulation of hemostasis and angiogenesis in cancer.
作者信息
Rak J, Klement G
机构信息
Hamilton Civic Hospital Research Centre, McMaster University, Hamilton, Ontario, Canada.
出版信息
Cancer Metastasis Rev. 2000;19(1-2):93-6. doi: 10.1023/a:1026516920119.
PMID:11191070
Abstract
We postulate that oncogenes and tumor suppressor genes may influence tumor angiogenesis not only directly (e.g. by upregulating vascular endothelial growth factor) but also through their impact on expression (and/or function) of tissue factor and other elements of the hemostatic system.
摘要
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