Moue Y, Kuwahira I, Iwamoto T, Kamio K, Hayashi Y, Ohta Y
Department of Emergency and Critical Care Medicine, Tokai University School of Medicine, Isehara, Kanagawa 259-1193, Japan.
Nihon Kokyuki Gakkai Zasshi. 2000 Nov;38(11):828-30.
A 44-year-old woman who had been treated for bronchial asthma for 5 years was admitted for further evaluation of progressive dyspnea. Physical examination revealed wheezing originating in the neck. A flow-volume curve suggested upper-airway stenosis. The patient had no history of trauma, endotracheal intubation, granulomatous diseases, or any other severe respiratory tract infections. Chest radiography and laboratory examination showed no abnormalities. Tracheal X-P, computed tomography and magnetic resonance imaging of the neck, and bronchoscopy demonstrated circumferential subglottic tracheal stenosis extending for 40 mm. The diameter of the lumen was 5 mm at its narrowest. The trachea distal to the lesion was normal. Bronchoscopic biopsy revealed thickened tracheal mucosa and submucosa with increased fibrous tissue and chronic inflammatory cell infiltration, suggesting a nonspecific inflammatory process. These findings are compatible with idiopathic tracheal stenosis, which was reported by Bhalla et al. The patient was treated with Nd-YAG laser surgery via a fiberoptic bronchoscope, which resulted in a great improvement in respiration. Regression of the lesion has not occurred in the 40 months since the laser surgery. The majority of patients with this condition have been treated by surgical resection of the stenotic lesion and reconstruction. However, the success of Nd-YAG laser surgery in the present case suggests that this approach would be a satisfactory alternative procedure for treatment of idiopathic tracheal stenosis.
一名患有支气管哮喘5年的44岁女性因进行性呼吸困难入院进一步评估。体格检查发现颈部有哮鸣音。流量-容积曲线提示上气道狭窄。患者无外伤、气管插管、肉芽肿性疾病或任何其他严重呼吸道感染史。胸部X线检查和实验室检查均无异常。气管X线平片、颈部计算机断层扫描和磁共振成像以及支气管镜检查显示环状声门下气管狭窄,长度达40 mm。管腔最窄处直径为5 mm。病变远端的气管正常。支气管镜活检显示气管黏膜和黏膜下层增厚,纤维组织增多,有慢性炎性细胞浸润,提示为非特异性炎症过程。这些发现与Bhalla等人报道的特发性气管狭窄相符。该患者通过纤维支气管镜接受了Nd-YAG激光手术治疗,呼吸状况有了很大改善。激光手术后40个月,病变未消退。大多数患有这种疾病的患者通过手术切除狭窄病变并进行重建治疗。然而,本例中Nd-YAG激光手术的成功表明,这种方法将是治疗特发性气管狭窄的一种令人满意的替代手术。