Gushi A, Hashiguchi T, Fukumaru K, Usuki K, Kanekura T, Kanzaki T
Department of Dermatology, Kagoshima University, Faculty of Medicine, Sakuragaoka 8-35-1 Kagoshima, 890-8520 Japan.
J Dermatol. 2000 Dec;27(12):778-81. doi: 10.1111/j.1346-8138.2000.tb02281.x.
We describe three cases of polyarteritis nodosa cutanea (PNC) showing necrotizing arteritis and only cutaneous lesions without systemic symptoms or visceral involvement for eleven, six, and three years after the onset of the disease. Since it was first described, there has been continuous controversy as to whether PNC progresses to systemic PN. Some cases have been described which had begun with a cutaneous lesion and progressed to the systemic form 19 and 18 years after the onset of the disease, so we believe that long term follow-up of this disease is essential.
我们描述了3例皮肤型结节性多动脉炎(PNC)病例,这些病例在发病后11年、6年和3年出现坏死性动脉炎,仅有皮肤病变,无全身症状或内脏受累。自首次描述以来,关于PNC是否会进展为系统性结节性多动脉炎一直存在争议。有一些病例被描述为起初有皮肤病变,在发病19年和18年后进展为系统性形式,因此我们认为对这种疾病进行长期随访至关重要。