Okumi M, Matsuoka Y, Tsukikawa M, Fujimoto N, Sagawa S, Itoh K
Department of Urology, Osaka Prefectural General Hospital.
Hinyokika Kiyo. 2000 Dec;46(12):887-90.
We report a case of a compound adrenal medullary tumor. A 63-year-old woman was referred to our hospital for examination of a right adrenal tumor, incidentally found by abdominal computed tomography (CT). CT and magnetic resonance imaging (MRI) revealed a round heterogeneous tumor, 5 cm in diameter, on the upper pole of the right kidney. A view of the total body scan demonstrated the uptake into the tumor after the injection of 123I-metaiodobenzyl-guanidine. Serum and urinary adrenaline levels were slightly elevated, and urinary excretion of vanillylmandelic acid was markedly elevated. Her blood pressure was normal. From these findings, the tumor was suspected to be a pheochromocytoma of the right adrenal gland and was resected reteroperitoneally. Pathological diagnosis was a compound adrenal medullary tumor, which was composed of pheochromocytoma and ganglioneuroma. This combination of the adrenal medullary tumor is extremely rare, and to date this case may be the sixth case in the Japanese medical literature.
我们报告一例复合性肾上腺髓质肿瘤。一名63岁女性因腹部计算机断层扫描(CT)偶然发现右肾上腺肿瘤而转诊至我院。CT和磁共振成像(MRI)显示右肾上极有一个直径5厘米的圆形不均匀肿瘤。全身扫描显示注射123I-间碘苄胍后肿瘤有摄取。血清和尿肾上腺素水平略有升高,香草扁桃酸尿排泄明显升高。她的血压正常。根据这些发现,怀疑该肿瘤为右肾上腺嗜铬细胞瘤,并经腹膜后切除。病理诊断为复合性肾上腺髓质肿瘤,由嗜铬细胞瘤和神经节神经瘤组成。这种肾上腺髓质肿瘤的组合极为罕见,迄今为止,该病例可能是日本医学文献中的第六例。