Rothenburger M, Tjan T D, Schmid C, Schmidt C, Schwarz T, Scheld H H
Department of Cardiothoracic Surgery, Westfalian Wilhelms-University, Muenster, Germany.
Ann Thorac Surg. 2001 Jan;71(1):349-51. doi: 10.1016/s0003-4975(00)02156-1.
A 68-year-old male patient developed pyoderma gangrenosum after elective aortic valve replacement. Treatment with steroids and clofazimine was initiated, which resulted in rapid cessation of the necrotic process. Due to thoracic instability, stabilization of the sternum was performed followed by surgical debridement and atraumatic wound closure. Postoperatively, immunosuppression with cyclosporine A was added; the patient recovered completely. Pyoderma gangrenosum is a potential life-threatening complication that must be considered in patients with severely impaired wound healing after cardiac operation.
一名68岁男性患者在择期主动脉瓣置换术后发生坏疽性脓皮病。开始使用类固醇和氯法齐明治疗，坏死过程迅速停止。由于胸廓不稳定，进行了胸骨固定，随后进行手术清创和无创伤伤口闭合。术后加用环孢素A进行免疫抑制治疗；患者完全康复。坏疽性脓皮病是一种潜在的危及生命的并发症，对于心脏手术后伤口愈合严重受损的患者必须予以考虑。
