Ohashi M, Fukunaga S, Kawano H, Tayama E, Kashikie H, Akashi H, Kawara T, Ohryoji A, Aoyagi S
Department of Surgery, Kurume University School of Medicine, 67 Asahi-machi, Kurume City, Fukuoka 830-0011, Japan.
Jpn J Thorac Cardiovasc Surg. 2001 Jan;49(1):47-52. doi: 10.1007/BF02913123.
Aging of the population is a current phenomenon in Japan, and life expectancy at 80 years old is getting longer. So we reviewed cardio-aortic operations on octogenarians at our institution.
Thirty-three consecutive octogenarian patients who had undergone cardio-aortic operations from 1992 to 1998 were studied. There were 14 men and 19 women. The mean age was 81.9 years. Of the 33, 19 patients (58%) were in New York Heart Association class IV, and 21 patients (64%) were operated on urgently or in emergency. The procedures undergone were operation for coronary artery disease in 17 patients, operation for valvular disease in 7 patients, operation for thoracic-aorta in 7 patients, and others in 2 patients.
The hospital mortality rate was 27% (9 patients). However, 89% of patients experiencing hospital death were in New York Heart Association class IV preoperatively and had required an emergency/urgent operation. On the other hand, there was only one hospital death (1/12, 8.3%) among the elective patients. The statistically significant risk factors for hospital death were renal insufficiency, shock, New York Heart Association class IV, intra-aortic balloon pumping, and longer cardiopulmonary bypass time. The one-, three-, and five-year-survival rate was 73%, 68%, and 55%, respectively. Of the survivors, 77% were in class I or II.
Although octogenarians' hospital mortality was still very high, the mid-term results were acceptable and the survivors' quality of life was satisfactory. These data suggested that we should operate on cardio-aortic patients before they reach a very serious state, especially in octogenarians.
人口老龄化是日本当前的一个现象,80岁老人的预期寿命越来越长。因此,我们回顾了我院对八旬老人进行的心脏主动脉手术。
研究了1992年至1998年连续接受心脏主动脉手术的33例八旬老人患者。其中男性14例,女性19例。平均年龄为81.9岁。在这33例患者中,19例(58%)为纽约心脏协会IV级,21例(64%)接受了急诊或紧急手术。所进行的手术包括17例冠状动脉疾病手术、7例瓣膜疾病手术、7例胸主动脉手术和2例其他手术。
医院死亡率为27%(9例)。然而,在医院死亡的患者中,89%术前为纽约心脏协会IV级,且需要急诊/紧急手术。另一方面,择期手术患者中只有1例医院死亡(1/12,8.3%)。医院死亡的统计学显著危险因素为肾功能不全、休克、纽约心脏协会IV级、主动脉内球囊反搏和较长的体外循环时间。1年、3年和5年生存率分别为73%、68%和55%。在幸存者中,77%为I级或II级。
尽管八旬老人的医院死亡率仍然很高,但中期结果是可以接受的,幸存者的生活质量也令人满意。这些数据表明,我们应该在心脏主动脉疾病患者病情尚未非常严重时进行手术,尤其是八旬老人。