Bir L S, Sermez Y, Türk T
Department of Neurology, Pamukkale University, Denizli, Turkey.
Electromyogr Clin Neurophysiol. 2001 Jan-Feb;41(1):49-52.
Although there are studies regarding the effects of thyroid hormones on some neurologic reflexes, literature lacks knowledge of the effects of thyroid hormones on blink reflex circuits. To understand the behaviour of excess thyroid hormone on this circuit that involves synapses in brainstem, we studied electrically elicited blink reflexes of 7 patients with hyperthyroidism, 8 patients with hyperthyroidism who were under therapy and 14 volunteers as control by electroneuromyograph. Mean values of the latencies and amplitudes of the R1 and R2 responses were not statistically different between groups, while the duration of R2 response and controlateral R2 response were found shorter in patients with hyperthyroidism comparing to the patients under therapy and controls. We have thought that these findings might reflect the inhibitor effect of the excess thyroid hormone on polysynaptic reflex arc of the blink response.
尽管有关于甲状腺激素对某些神经反射影响的研究,但文献中缺乏甲状腺激素对瞬目反射回路影响的相关知识。为了解过量甲状腺激素对这个涉及脑干突触的回路的作用,我们通过肌电图对7例甲状腺功能亢进患者、8例正在接受治疗的甲状腺功能亢进患者以及14名志愿者作为对照进行了电诱发瞬目反射研究。R1和R2反应的潜伏期和波幅的平均值在各组之间无统计学差异,而甲状腺功能亢进患者的R2反应及对侧R2反应的时长与接受治疗的患者及对照组相比更短。我们认为这些发现可能反映了过量甲状腺激素对瞬目反应多突触反射弧的抑制作用。