萘啶酸引起的大疱性光反应。
Bullous photoreaction to nalidixic acid.
作者信息
Brauner G J
出版信息
Am J Med. 1975 Apr;58(4):576-80. doi: 10.1016/0002-9343(75)90134-5.
PMID:1124793
Abstract
Curtaneous blisters developed after exposure to the sun in two women who were taking nalidixic acid. Blisters continued to appear even after therapy was discontinued and there was no further exposure to the sun. Phototesting showed abnormal sensitivity to both short and long wavelength ultraviolet spectra in one patient. The low incidence of this phenomenon suggests a photoallergic mechanism, but features of both photoallergy and phototoxicity are present.
摘要
两名正在服用萘啶酸的女性在日晒后出现皮肤水疱。即使停止治疗且不再暴露于阳光下，水疱仍持续出现。光试验显示一名患者对短波和长波紫外线光谱均有异常敏感性。这种现象的低发生率提示为光过敏机制，但同时存在光过敏和光毒性的特征。
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