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[一例凸面扁平脑膜瘤病例]

[A case of convexity meningioma en plaque].

作者信息

Matsushige T, Yoshioka H, Okita S, Yamasaki F, Sugiyama K, Arita K, Kurisu K

机构信息

Department of Neurosurgery, Hiroshima University.

出版信息

No Shinkei Geka. 2001 Feb;29(2):145-50.

Abstract

We present a case of convexity meningioma en plaque (MEP). A 51-year-old male occasionally suffering from right parietalgia and numbness of left upper limb. An intracranial abnormal mass was pointed out incidentally by the brain check up. Computed tomographic (CT) scans demonstrated a hyperostosis and an enhanced abnormal mass at the right front-parietal region. Magnetic resonant images (MRI) revealed a carpet like tumor extended along the dura mater. Cerebral angiography disclosed feedings from parietal branches of right middle meningeal artery and superficial temporal artery. The tumor was removed subtotally with adjacent dura mater, leaving the portion of close adhesion to the brain parenchyma. Histologic diagnosis was transitional meningioma. Immunohistological stainings showed a high staining index (6.9%) of MIB-1 (Ki-69 antigen) and high expression of metalloproteinase-9 (MMP-9), especially along the dura mater. Convexity MEP is so rare that we review previous reported cases of convexity MEP, and discuss the clinicopathologic features on that.

摘要

我们报告一例凸面脑膜瘤斑块状(MEP)病例。一名51岁男性,偶尔出现右顶叶疼痛和左上肢麻木。脑部检查偶然发现颅内异常肿块。计算机断层扫描(CT)显示右额顶叶区域有骨质增生和强化异常肿块。磁共振成像(MRI)显示一个沿硬脑膜延伸的地毯样肿瘤。脑血管造影显示由右脑膜中动脉顶支和颞浅动脉供血。肿瘤与相邻硬脑膜一起次全切除,留下与脑实质紧密粘连的部分。组织学诊断为过渡型脑膜瘤。免疫组织化学染色显示MIB-1(Ki-69抗原)的高染色指数(6.9%)和金属蛋白酶-9(MMP-9)的高表达,尤其是沿硬脑膜。凸面MEP非常罕见,因此我们回顾了既往报道的凸面MEP病例,并讨论了其临床病理特征。

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