Falk V, Diegeler A, Walther T, Löscher N, Vogel B, Ulmann C, Rauch T, Mohr F W
Department of Cardiac Surgery, Heartcenter, University of Leipzig, Germany.
Heart Surg Forum. 1999;2(3):199-205.
To develop a technique for computer enhanced endoscopic arterial bypass grafting on the beating heart in an experimental canine model.
Mongrel dogs (30-35 kg) were used. After single lung ventilation of the right lung was initiated the dogs were placed to the right. The videoscope and the end-effectors of the da Vinci telemanipulation system (Intuitive Surgical, Mountain View, CA) were introduced through three ports. Surgery was performed remotely from the console (motion scaling 3:1). After harvesting of the internal thoracic artery (ITA) and preparation of its distal end, the Endostab, a newly developed endoscopic stabilizer, was introduced through an additional port. The anterior wall of the heart was stabilized and the collateral branch (RC) of the left anterior descending artery (LAD) was ligated proximally and distally. The arteriotomy was made and the ITA-graft anastomosed to the RC. The animals were sacrificed and the grafts were checked for patency using bench angiography.
In two of five dogs total endoscopic beating heart bypass grafting, including ITA harvest, stabilization, arteriotomy and performance of the anastomosis, was successfully performed using computer enhanced technology and a new endoscopic stabilizer. In two dogs the procedure was completed with femoro-femoral cardiopulmonary bypass (CPB) support on the beating or fibrillating heart, respectively. One dog expired due to VT. Hemodynamically, endoscopic stabilization was well tolerated. All four grafts were patent despite a target vessel diameter of less than 1 mm.
The endoscopic stabilizer can sufficiently immobilize the heart to enable endoscopic beating heart coronary artery bypass grafting by means of a computer controlled instrumentation system.
在实验犬模型中开发一种用于在跳动心脏上进行计算机增强型内镜动脉搭桥术的技术。
使用杂种犬(30 - 35千克)。在开始右肺单肺通气后,将犬置于右侧。通过三个端口引入达芬奇远程操作系统(直观外科公司,加利福尼亚州山景城)的视频内窥镜和末端执行器。在控制台远程进行手术(运动缩放比例为3:1)。在获取胸廓内动脉(ITA)并准备其远端后,通过一个额外的端口引入一种新开发的内镜稳定器Endostab。稳定心脏前壁,在左前降支动脉(LAD)的侧支分支(RC)的近端和远端进行结扎。进行动脉切开术,并将ITA移植物与RC进行吻合。处死动物,使用台式血管造影检查移植物的通畅情况。
在五只犬中的两只中,使用计算机增强技术和一种新的内镜稳定器成功进行了全内镜下跳动心脏搭桥术,包括ITA获取、稳定、动脉切开术和吻合操作。在另外两只犬中,分别在跳动或颤动的心脏上使用股-股体外循环(CPB)支持完成了手术。一只犬因室性心动过速死亡。从血流动力学角度看,内镜稳定耐受性良好。尽管目标血管直径小于1毫米,但所有四个移植物均通畅。
内镜稳定器能够充分固定心脏,以便通过计算机控制的器械系统进行内镜下跳动心脏冠状动脉搭桥术。