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组胺——它会引发急性冠状动脉事件吗?

Histamine--can it cause an acute coronary event?

作者信息

Gupta M K, Gupta P, Rezai F

机构信息

Department of Cardiology, Jersey City Medical Center, Mount Sinai School of Medicine, New Jersey, USA.

出版信息

Clin Cardiol. 2001 Mar;24(3):258-9. doi: 10.1002/clc.4960240317.

Abstract

Myocardial infarction (MI) occurring during the course of an allergic urticarial reaction in the absence of systemic hypotension has been rarely reported. This paper reports the case of a 28-year-old woman with no significant risk factors for coronary artery disease who presented with generalized urticaria associated with chest pain and had electrocardiographic and enzymatic evidence of an acute MI. Review of the literature suggests that local histamine release may induce spasm of the coronary vasculature, thus leading to myocardial ischemia and infarction.

摘要

在无系统性低血压的情况下,于过敏性荨麻疹反应过程中发生心肌梗死(MI)的情况鲜有报道。本文报告了一例28岁女性病例,该患者无明显冠状动脉疾病危险因素,出现伴有胸痛的全身性荨麻疹,并有急性心肌梗死的心电图和酶学证据。文献回顾表明,局部组胺释放可能诱发冠状动脉血管痉挛,从而导致心肌缺血和梗死。

相似文献

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本文引用的文献

3
Role of cardiac mast cells in complement C5a-induced myocardial ischemia.
Am J Physiol. 1993 May;264(5 Pt 2):H1346-54. doi: 10.1152/ajpheart.1993.264.5.H1346.
4
Acute allergic reaction with coronary vasospasm.伴有冠状动脉痉挛的急性过敏反应。
Am Heart J. 1982 May;103(5):928. doi: 10.1016/0002-8703(82)90419-7.
7
Histamine receptors in the human heart.人类心脏中的组胺受体。
Life Sci. 1980 Jun 30;26(26):2245-9. doi: 10.1016/0024-3205(80)90209-x.
9
Acute myocardial infarction after a wasp sting.黄蜂蜇伤后急性心肌梗死
Br Heart J. 1988 Apr;59(4):506-8. doi: 10.1136/hrt.59.4.506.

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