Wiest G H, Foerst J, Fuchs F S, Lampert S, Schahin S P, Fuchs T O, Hahn E G, Ficker J H
Bereich Pneumologie, Medizinische Klinik I mit Poliklinik, Erlangen sowie.
Dtsch Med Wochenschr. 2001 Mar 16;126(11):294-8. doi: 10.1055/s-2001-11878.
Upper airway dryness is a frequent side-effect of nasal continuous positive airway pressure (nCPAP) therapy in obstructive sleep apnoea syndrome (OSA). In this situation, heated humidification is often used. Therefore, the present study aimed to investigate the humidification performance--defined as the maximum achievable humidity in the tube system of the CPAP device--of a heated humidifier (HH) offered as CPAP accessories, as a function of ambient air conditions (humidity and temperature).
In 30 patients (22 male, 8 female, mean age 56.4 +/- 11.7 years) with OSA undergoing CPAP treatment, temperature (T) and relative humidity (RH) in the CPAP tube system were measured, with and without the HH Somnowave, until a steady state was achieved. At the same time, ambient T and RH in the examination room were recorded. T and RH were used to calculate the absolute humidity (AH).
The conditions of the examination room during the examination nights were as follows: T = 21.9 +/- 2.8 degrees C (15.2-26.9), RH 46.5 +/- 11.9% (21.7-69.1) and AH 9.2 +/- 3.2 g/m3 (3.7-16.7). The steady state AH without HH was 9.6 +/- 3.0 g/m3 (4.1-15.4), that with HH (humidification performance) 23.2 +/- 2.8 g/m3 (19.1-29.9) (p < 0.001).
Under the ambient conditions of humidity and temperature, commonly found in European bedrooms, the HH demonstrate a high humidification performance. Thus, it would appear that the HH is suitable for the treatment of dry upper airways under nCPAP therapy.
上气道干燥是阻塞性睡眠呼吸暂停综合征(OSA)患者鼻持续气道正压通气(nCPAP)治疗常见的副作用。在这种情况下,常采用加热湿化。因此,本研究旨在探讨作为CPAP配件提供的加热湿化器(HH)的湿化性能(定义为CPAP设备管路系统中可达到的最大湿度)与环境空气条件(湿度和温度)之间的关系。
对30例接受CPAP治疗的OSA患者(22例男性,8例女性,平均年龄56.4±11.7岁),在使用和不使用HH Somnowave的情况下,测量CPAP管路系统中的温度(T)和相对湿度(RH),直至达到稳定状态。同时,记录检查室的环境温度和相对湿度。利用温度和相对湿度计算绝对湿度(AH)。
检查夜间检查室的条件如下:温度=21.9±2.8℃(15.2 - 26.9),相对湿度46.5±11.9%(21.7 - 69.1),绝对湿度9.2±3.2g/m³(3.7 - 16.7)。不使用HH时的稳定状态绝对湿度为9.6±3.0g/m³(4.1 - 15.4),使用HH时(湿化性能)为23.2±2.8g/m³(19.1 - 29.9)(p<0.001)。
在欧洲卧室常见的湿度和温度环境条件下,HH表现出较高的湿化性能。因此,HH似乎适用于nCPAP治疗下对上气道干燥的治疗。